Mānusikadukkhanti manussesu vadhabandhanādikaṃ dukkhaṃ. Gabbhokkantimūlakadukkhanti "ayaṃ hi satto mātukucchimhi nibbattamāno na uppalapadumapuṇḍarikādīsu nibbattatī"tiādinā nayena yaṃ jātidukkhaṃ vuttaṃ, idaṃ tāva gabbhokkantimūlakadukkhaṃ anveti. Gabbhe ṭhitimūlakadukkhanti yaṃ pana "so mātu sahasā upakkhalanagamananisīdanavuṭṭhāna- parivattanādīsū"tiādinā nayena yaṃ tibbaṃ dukkhaṃ vuttaṃ, idaṃ gabbhe ṭhitimūlakaṃ dukkhaṃ anveti. Gabbhavuṭṭhānamūlakadukkhanti "yaṃ panassa mūḷhagabbhāya mātuyā mittāmaccasuhajjādīhi adassanārahe dukkhuppattiṭṭhāne"tiādinā nayena yaṃ dukkhaṃ vuttaṃ, idaṃ mātukucchito bahi nikkhantamūlakaṃ dukkhaṃ anveti. Tenetaṃ vuccati:-

"yañcāpi gūthanarake viya mātugabbhe

satto vasaṃ ciramato bahi nikkhamanañca

pappoti dukkhamatighoramidampi natthi